梯队公司/Sn(IV)原卟啉IX/250mg/F-H080-250mg
商品编号:
F-H080-250mg
品牌:
联合碳化
市场价:
¥2640.00
美元价:
1386.00
产品分类:
脂质代谢研究
公司分类:
Lipid_metabolism_study
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
CatalogNo.: F-H080 MW: 750.26 Description: Sn(IV)ProtoporphyrinIXisaninhibitorhemeoxygenase(theenzymethatcatalyzestheconversionofhemetobiliverdininthehemedegradationpathway)buthasalsobeenfoundtostimulateproductionofthehemeoxygenaseprotein.ContrasttheactivityofCo(III)ProtoporphyrinwhichhasbeenfoundtohavesimilaractivitiestoSn(IV)ProtoporphyrinbutwithagreaterenhancementofhemeoxygenasesynthesisactivitysuchthathemeoxygenaseactivityisactuallyincreasedwhenadmiNISTeredinvivowhileinvitroadministrationinhibitshemeoxygenaseactivity.Hemeoxygenasehasbeenimplicatedintumorcellresistancetochemotherapy,reductionoffreerADIcalformationandinflammation,andassociatedwithvascularrepair. | |||
StorageSn(IV)ProtoporphyrinIXisstableforatleastoneyearwhenstoredasasolid,protectedfrommoisture,at-20°C.Protectfromlight.References1)Sardana,M.K.andA.Kappas(1987)."Dualcontrolmechanismforhemeoxygenase:tin(IV)-protoporphyrinpotentlyinhibitsenzymeactivitywhilemarkedlyincreasingcontentofenzymeproteininliver."ProcNatlAcadSciUSA84(8):2464-8.2)Jozkowicz,A.,H.Was,etal.(2007)."Hemeoxygenase-1intumors:isitafalsefriend?"AntioxidRedoxSignal9(12):2099-117. 3)Abraham,N.G.andA.Kappas(2005)."Hemeoxygenaseandthecardiovascular-renalsystem."FreeRadicBiolMed39(1):1-25. 4)Kim,D.H.,A.P.Burgess,etal.(2008)."Hemeoxygenase-mediatedincreasesinadiponectindecreasefatcontentandinflammatorycytokinestumornecrosisfactor-alphaandinterleukin-6inZuckerratsandreduceAdipogenesisinhumanmesenchymalstemcells."JPharmacolExpTher325(3):833-40. |
品牌介绍
Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14