4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
联合碳化(授权代理)
主营:实验室透析袋
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Lipid_metabolism_study > echelon-inc/Sphingosine-1-Phosphate Lyase Overexpression Lysate, active/250ug/E-5000L-250ug
商品详细echelon-inc/Sphingosine-1-Phosphate Lyase Overexpression Lysate, active/250ug/E-5000L-250ug
echelon-inc/Sphingosine-1-Phosphate Lyase Overexpression Lysate, active/250ug/E-5000L-250ug
echelon-inc/Sphingosine-1-Phosphate Lyase Overexpression Lysate, active/250ug/E-5000L-250ug
商品编号: E-5000L-250ug
品牌: 联合碳化
市场价: ¥5000.00
美元价: 2500.00
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Zoom
 
CatalogNo.: E-5000L

Description: Sphingsoine-1-phosphatelyase(SPL)(E.C.4.1.2.27)worksasakeyregulatorofthefinalstepofthesphingolipiddegradativepathwaybyirreversIBLybreakingdownthesphingosine-1-phosphate(S1P)toethanolaminephosphateandhexadecenal.S1PsignalingthroughitsfivereceptorsinvolvesinmanyBIOLOGicaleventssuchasproliferation,inflammationandapoptosisincancerandotherdegenerativediseases.

HEK293celllysatewithoverexpressedSPL-GFP(greenfluorescentprotein).

Storage

-80°C.Theenzymeisstablefor6monthsfromthedateofreceipt.Avoidrepeatfreezethawcycles.

References

1.Billich,A.,etal.(2013)."Partialdeficiencyofsphingosine-1-phosphatelyaseconfersprotectioninexperimentalautoimmuneencephalomyelitis."PLoSOne8(3):e59630.
2.Engel,N.,etal.(2012)."Metabolicprofilingrevealssphingosine-1-phosphatekinase2andlyaseaskeytargetsof(phyto-)estrogenactioninthebreastcancercelllineMCF-7andnotinMCF-12A."PLoSOne7(10):e47833.
3.Bedia,C.,etal.(2009)."Synthesisofafluorogenicanalogueofsphingosine-1-phosphateanditsusetodeterminesphingosine-1-phosphatelyaseactivity."Chembiochem10(5):820-2.
4.Reiss,U.,etal.(2004)"Sphingosine-phosphateLyaseEnhancesStress-inducedCeramideGenerationandApoptosis."J.Biol.Chem.279(2):1281-1290.

Relatedproducts
Sphingosine-1-PhosphateLyaseFluorogenicSubstrate(S-200U)
2-Acetyl-5-tetrahydroxybutylimidazole(THI)(B-0031)
Sphingolipids
Sphingosine1-PhosphateELISAkit(K-1900)

品牌介绍
Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14