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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > 梯队公司/Src,现行/5ug/E-K051-5ug
商品详细梯队公司/Src,现行/5ug/E-K051-5ug
梯队公司/Src,现行/5ug/E-K051-5ug
梯队公司/Src,现行/5ug/E-K051-5ug
商品编号: E-K051-5ug
品牌: 联合碳化
市场价: ¥5260.00
美元价: 2498.50
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

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CatalogNo.: E-K051

Description: RecombinantfulllengthRoussarcomavirusSrcproteincontainingN-terminalGSTtagwasexpressedbybaculovirusinSf9insectcells.
ThegeneaccessionnumberisM11753.
Thismaterialissoldforresearchpurposesonly.
SpecificActivity
116nmolphosphateincorporatedintoSrcsubstratepeptideperminutepermgproteinsat300Cfor15minutesusingafinalconcentrationof50µMATP(0.83µCi/assayin25ulreactionvolume).

ScientificBackground

  • Srcfamilybelongstonon-receptortyrosinekinases.SrcwasoriginallyidentifiedasatransformingproteinoftheRoussarcomavirus(RSV)thathadenzymaticABIlitytophosphorylatetyrosineinproteinsubstrates.Srcisoverexpressedandactivatedinalargenumberofhumanmalignanciesandhasbeenlinkedtothedevelopmentofcancerandprogressiontodistantmetastases.Inadditiontoincreasingcellproliferation,akeyroleofSrcincancerseemstobetheabilitytopromoteinvasionandmotility,functionsthatmightcontributetotumourprogression.OncogenicformsoftheSrcaltercellstructure,inparticulartheactinCytoskeletonandtheadhesionnetworksthatcontrolcellmigration,andalsotransmitsignalsthatregulateproliferationandcellsurvival.RecentworkindicatesthatSrcplaysaroleinthesefunctionsbyinfluencingtheRhoA-ROCKpathwaythatcontrolscontractileactinfilamentassembly,theSTATfamilyoftranscriptionfactorsneededfortransformation,andtheCblubiquiti

    Storage

    • Storeproductfrozenatorbelow-70°C.Stablefor1yearat-70°Casundilutedstock.Aliquottoavoidrepeatedthawingandfreezing.
    品牌介绍
    Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14