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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > echelon-inc/Akt Inhibitor (FPA-124)/5mg/B-0101-5mg
商品详细echelon-inc/Akt Inhibitor (FPA-124)/5mg/B-0101-5mg
echelon-inc/Akt Inhibitor (FPA-124)/5mg/B-0101-5mg
echelon-inc/Akt Inhibitor (FPA-124)/5mg/B-0101-5mg
商品编号: B-0101-5mg
品牌: 联合碳化
市场价: ¥1360.00
美元价: 714.00
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

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CatalogNo.: B-0101
MW: 381.7
Purity: 99%
CAS: 902779-59-3

Description: FPA-124isacell-permeableinhibitorofAkt(IC50=100nM),bindingtothePHandkinasedomains.ItinhibitscellproliferationinColo357,BxPC3,BT20,andPC3cancercelllineswithIC50valuesrangingfrom7-55nM.FPA-124inhibitedtumorgrowthinmicewithnegligIBLetoxicity.

Solubility

DMSO:5mg/mL

Storage

Storedrybetween2-8oC.Stocksolutionsshouldbestoredfrozen(-20oC).

References

1)V.Barve,etal.“Synthesis,MolecularCharacterization,andBIOLOGicalActivityofNovelSynthetic
DerivativesofChromen-4-oneinHumanCancerCells”J.Med.Chem.,2006,49,3800-3808.
2)Biscetti,F.,G.Straface,etal.(2009)."PioglitazoneenhancescollateralbloodflowinischemichindlimbofdiabeticmicethroughanAkt-dependentVEGF-mediatedmechanism,regardlessofPPARgammastimulation."CardiovascDiabetol8:49.
3)Brito,P.M.,R.l.Devillard,etal.(2009)."ResveratrolinhibitsthemTORmitogenicsignalingevokedbyoxidizedLDLinsmoothmusclecells."Atherosclerosis205(1):126.

品牌介绍
Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14