echelon-inc/Akt Inhibitor (FPA-124)/5mg/B-0101-5mg
商品编号:
B-0101-5mg
品牌:
联合碳化
市场价:
¥1360.00
美元价:
714.00
产品分类:
脂质代谢研究
公司分类:
Lipid_metabolism_study
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
CatalogNo.: B-0101 MW: 381.7 Purity: 99% CAS: 902779-59-3 Description: FPA-124isacell-permeableinhibitorofAkt(IC50=100nM),bindingtothePHandkinasedomains.ItinhibitscellproliferationinColo357,BxPC3,BT20,andPC3cancercelllineswithIC50valuesrangingfrom7-55nM.FPA-124inhibitedtumorgrowthinmicewithnegligIBLetoxicity. | |||
SolubilityDMSO:5mg/mLStorageStoredrybetween2-8oC.Stocksolutionsshouldbestoredfrozen(-20oC).References1)V.Barve,etal.“Synthesis,MolecularCharacterization,andBIOLOGicalActivityofNovelSyntheticDerivativesofChromen-4-oneinHumanCancerCells”J.Med.Chem.,2006,49,3800-3808. 2)Biscetti,F.,G.Straface,etal.(2009)."PioglitazoneenhancescollateralbloodflowinischemichindlimbofdiabeticmicethroughanAkt-dependentVEGF-mediatedmechanism,regardlessofPPARgammastimulation."CardiovascDiabetol8:49. 3)Brito,P.M.,R.l.Devillard,etal.(2009)."ResveratrolinhibitsthemTORmitogenicsignalingevokedbyoxidizedLDLinsmoothmusclecells."Atherosclerosis205(1):126. |
品牌介绍
Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14