梯队公司/Akt抑制剂（KP372-1）/5mg/B-0102-5mg
商品编号：
B-0102-5mg
品牌：
联合碳化
市场价：
¥5960.00
美元价：
2831.00
产品分类：
脂质代谢研究
公司分类：
Lipid_metabolism_study
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
 | CatalogNo.: B-0102 MW: 224.2 Purity: 95% CAS: 329710-24-9 Description: KP372-1directlyinhibitsthekinaseactivitiesofAkt,PDK1andFlt3(Fms-liketyrosinekinase3),whichareaberrantlyactivatedinacutemyelogenousleukemia(AML).Itisacellpermeantinhibitorthatdecreasesthecolony-formingABIlityofAMLcells(IC50< 200 nM) with minimal cytoxic effects on normal hematopoietic Progenitorcells.KP372-1hasalsobeenshowntosuppresscellproliferationandinduceapoptosisinthyroidcancercellsandgliobastoma. | ||
SolubilityWater:insoluble,DMSO:5mg/mLStoragedrybetween2-8oC.Stocksolutionsshouldbestoredfrozen(-20oC).References1)M.Mandaletal.“TheAktInhibitorKP372-1SuppressesAktActivityandCellProliferationandInducesApoptosisinThyroidCancerCells”Br.J.Cancer,2005,92,1899-1905. 2)Z.Zengetal“SimultaneousInhibitionof PDK1/AKTandFms-LikeTyrosineKinase3SignalingbyaSmall-MoleculeKP372-1InducesMitochondrial DysfunctionandApoptosisinAcuteMyelogenousLeukemia.”CancerRes.,2006,66,3737-3746. | |||
品牌介绍
Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25（3500）/25mm/MD25-3.5MD25-3.5透析透析1543.14
