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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > echelon-inc/DBPC (PLA2 Substrate)/100ug/L-3000-100ug
商品详细echelon-inc/DBPC (PLA2 Substrate)/100ug/L-3000-100ug
echelon-inc/DBPC (PLA2 Substrate)/100ug/L-3000-100ug
echelon-inc/DBPC (PLA2 Substrate)/100ug/L-3000-100ug
商品编号: L-3000-100ug
品牌: 联合碳化
市场价: ¥4620.00
美元价: 2310.00
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

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CatalogNo.: L-3000
CAS: 885331-21-5

Description: ThePLA2substrateDBPC,isasensitiveprobeforacontinuousfluorogenicdetectionapplicabletoboth/invitro/andcell-based/insitu/screeningassays

PhospholipaseA2(PLA2)istheenzymewhichcleavesphospholipidstoproducelysophospholipidsandfreefattyacids.ThePLA2familyofenzymesisknowntobeatleast10distinctmembers.sPLA2-VandsPLA2-XareselectivelyexpressedinhumanairwayepitheliumandsPLA2-Xinvariousimmunecells.Thebasalexpressionofathirdenzyme,sPLA2-IIAislowbutbecomeshighlyexpressedduringinflammationandsepsis.Thisenzymehasbecomeassociatedwithallergicrhinitis,rheumatoidarthritis,septicshockandARDS.PLA2-IIArepresentsatargetforthetreatmentofinflammatorydisease.

Storage

-20°Cprotectedfromlight

FeaturedinPublications

1)Zhao,X.,D.Wang,etal.(2006)."Caspase-3-dependentactivationofcalcium-independentphospholipaseA2enhancescellmigrationinnon-apoptoticovariancancercells."JBiolChem281(39):29357-68.
2)Manna,D.,W.Cho,etal.(2007).Real-TimeCellAssaysofPhospholipaseA2sUsingFluorogenicPhospholipids.MethodsinEnzymology,AcademicPress.Volume434:15.
3)Cai,Q.,Z.Zhao,etal.(2012)."ElevatedandsecretedphospholipaseA2activitiesasnewpotentialtherapeutictargetsinhumanepithelialovariancancer."TheFASEBJournal26(8):3306-3320.

Keywords:DBPC,Bodipy,PLA2,phospholipase

品牌介绍
Viskase常用产品报价单产品名货号公司分类商城分类美金价Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14